BLINK
Fold recognition system
Description:
The BLast-INduced Konsensus (BLINK) searches for distant sequence homologues of the query sequence. This is done by selecting, in a meta-server fashion, the top-scoring target among the best alignments generated by three methods: two sequence-profile-based algorithms, namely PSI-BLAST and RPSBLAST, and BLASTP (a sequence-sequence-based method). Although BLINK is not the most sensitive fold recognition method, it is convenient for interactive use and preliminary screening since it is fast, the most time-consuming step being the PSI-BLAST run used to generate the sequence profile of the input protein. The method is very similar to those described in Wallner et al. [Proteins 54 (2004) 342-350]
